To simplify the expression 45,27:2,34, we need to perform the division operation first, then the addition operation.

First, divide 27 by 2:
27 ÷ 2 = 13.5

Now, add 45 to the result:
13.5 + 45 = 58.5

Finally, add 34 to the previous result:
58.5 + 34 = 92.5

Therefore, 45,27:2,34 simplifies to 92.5.