d. b or c

Sentence: In spite of his physical handicap, he has become a successful businessman.

Explanation: Both "In spite of" and "Despite" can be used to indicate that something happened regardless of the physical handicap.

c. but

Sentence: I like bananas, but my brother doesn’t.

Explanation: "But" is used to contrast between what I like and what my brother doesn’t.

a. so

Sentence: It's raining, so I can't go to the beach.

Explanation: "So" indicates the result or consequence of it raining.

a. but

Sentence: It was still painful, but I went to see a doctor.

Explanation: "But" is used to show a contrast between the pain and the decision to see a doctor.

c. so

Sentence: He felt ill so he went to bed early.

Explanation: "So" indicates the result of feeling ill, which was going to bed early.

a. moreover

Sentence: He was the best in class at Maths and English; moreover, he was the best footballer in the school.

Explanation: "Moreover" adds additional information, emphasizing that he was the best in more than one area.

b. however

Sentence: Geography is a very interesting subject; however, very few people study it thoroughly.

Explanation: "However" introduces a contrast between the interest in the subject and the lack of thorough study.

d. so

Sentence: It was very wet so I decided not to go.

Explanation: "So" indicates the consequence of the wet weather.

b. Despite

Sentence: Despite the severe weather conditions, all the cars completed the course.

Explanation: "Despite" is used to show that the action occurred regardless of the severe weather conditions.

c. but

Sentence: Jane has a computer, but she doesn't use it.

Explanation: "But" is used to contrast having a computer with not using it.

c. but

Sentence: I’d love to play volleyball but I have to complete an assignment.

Explanation: "But" is used to contrast the desire to play volleyball with the obligation to complete an assignment.

a. therefore

Sentence: Lan failed her English; therefore, she has to do the test again.

Explanation: "Therefore" indicates the logical consequence of failing the English test.

d. therefore

Sentence: Minh got wet; therefore, he forgot his raincoat.

Explanation: "Therefore" is used to indicate the result of getting wet, which was forgetting the raincoat.

b. in case

Sentence: I’ll bring a raincoat in case it rains.

Explanation: "In case" is used to express preparation for a possible future event.

c. though

Sentence: My father has to go to work though it is raining hard.

Explanation: "Though" is used to indicate that the necessity to go to work persists despite the heavy rain.