1. Despite having flu, she insisted on going out(yet)
->........She had fly yet she insisted on going out ......
2. Although the weather was changed, the picnic went ahead as plannned (spite)
-> The picnic went ahead as plannned ..............in spite of the changed weather....................in the weather.
3. In spite of her initial reluctance to take the job, she's got on very well.
-> Reluctant...........to take the job might be at first, she's got on very well.....
4. I admit he 's clever, but I don't think he'll solve this problem.
-> However.....................clever is he,I don't think he'll solve this problem...........................................
5. He managed to complete the sculpture although his eyesight was failing.
-> Despite.......... his failing eyesight ,He managed to complete the sculpture..................
6. Although it rained torrentially all day, we all enjoyed the excursion
-> Despite.............raninning torrentially all day, we all enjoyed the excursion...................................