My sister will take a plane even though she dislikes flying.

>>In spite of the fact that she dislikes flying, my sister will.... 

He isn’t happy although he is very rich. 

>>Despite being very rich, he isn't happy 

Even though he got a good job, he was not satisfied

>> Despite gotting a good job, he was not satisfied 

Although he tells lies, many people believe him.
Despite the fact that he tell lies, mamany people....