To solve the equation \((x - 16.2) - 3.24 = 0.121 \times 100\), follow these steps:

1. Simplify the right-hand side of the equation:
\[
0.121 \times 100 = 12.1
\]

2. Substitute this value back into the equation:
\[
(x - 16.2) - 3.24 = 12.1
\]

3. Combine the constants on the left-hand side:
\[
x - 16.2 - 3.24 = 12.1
\]
\[
x - 19.44 = 12.1
\]

4. Isolate \(x\) by adding 19.44 to both sides of the equation:
\[
x - 19.44 + 19.44 = 12.1 + 19.44
\]
\[
x = 31.54
\]

So, the solution to the equation is:
\[
x = 31.54
\]