41. It doesn’t matter how hard she tries, she never beat Sue at tennis.
=> However.. hard she tries, she never beat Sue at tennis

42. No matter what he says, nobody believes him.

=> Whatever...he says, nobody believes him..................................................................................

43. He always woke up early no matter how late he had gone to bed.
=> However.............late he had gone to bed, he always woke up early.........................................................................

44. Melissa’s father was very busy, but he still played with her.
=> Busy...as Melissa’s father was, he still played with her.........................................................................................

45. She didn’t eat much though she was hungry.

=>In spite of . being hungry, she didn’t eat much............................................................................................................................................

46. Although he had much experience in machinery, he didn’t succeed in repairing this machine.

=> Despite ..having much experience in machinery, he didn’t succeed in repairing this machine...........................................................................................................................................

47. We did the test well though it was difficult.

=>In spite of ..the difficult test, we did it well...........................................................................................................................................

48. Although he is strong, I’m not afraid of him.

=> Despite ... the fact that he is strong, I’m not afraid of him..........................................................................................................................................

49. The plane took off though the weather was bad.

=>In spite of ..... the bad weather, the plane took off........................................................................................................................................

50. Though his English was good, he wasn’t chosen.

=> Despite ...

 his good English, he wasn’t chosen