1. Although Mai did not speak English well, she decided to live in London.
In spite of not speaking English well, she decided to live in London.

2. In spite of the cold weather, we all wore shorts.
Even though the weather was cold, we all wore shorts.

3. In spite of her beauty and intelligence, nobody likes her.
Though she is beautiful and intelligent, nobody likes her.

4. In spite of playing well, our team lost the game.
Although we played well, our team lost the game.