Here are the correct answers for the blanks:

1. She isn't very popular. She has few friends.


2. Ann is very busy these days. She has little free time.


3. Did you take many pictures when you were on holiday?


4. I'm not very busy today. I don't have much to do.


5. This is a very modern city. There are few old buildings.


6. A large number of people attended the conference.


7. 'Do you know Rome?' 'No, I haven't been there for a few years.'


8. Gary is very busy with his job. He has little time for other things.


9. Listen carefully. I'm going to give you a little advice.


10. Do you mind if I ask you a few questions?



Explanation:

Few and many are used with countable nouns.

Little and much are used with uncountable nouns.

A few and a little suggest a small but positive quantity.

A large number of is used for countable nouns when referring to a large quantity.