Sure, here are the answers filled in:

1. The phone last rang at four o’clock. ~ So you’ve had no calls **since**?
2. I haven’t been to the dentist for ten years. ~ You last went to the dentist **ten years ago**?
3. I last saw Rita on Sunday. ~ Haven’t you seen her **since**?
4. We’ve had six weeks without rain. ~ Yes, it hasn’t rained **for six weeks**.
5. It’s three years since Lisa got married. ~ Really? Has she been married **for three years**?
6. It’s eight months since my sister had any work. ~ He lost his job **eight months ago**?
7. Mrs. Brown was taken ill three weeks ago. ~ You mean she’s been ill **for three weeks**, and nobody’s told me!
8. I got here an hour ago. ~ What! You mean you’ve been waiting **for** an hour?
9. I have not seen him **since** he was 16.
10. I've known him **for** ages.
11. Things have changed a lot **since** our previous meeting.
12. It's been raining **since** four o'clock.
13. I'm sure he's been watching us **since** we came in.
14. He'd been here **for** over an hour when we arrived.
15. I've been trying to fix this computer **since** early this morning.
16. He hasn't had anything to eat **for** nearly a week.
17. It's three years **since** he started learning German.
18. He's been collecting stamps **for** the past twenty years.
19. Nobody has seen him **since** last Friday.
20. It has been foggy **for** some days.
21. He has been fishing **since** six o'clock.
22. They've been living in France **for** eight years.
23. The pilots have been on strike **for** two months.
24. We've had terrible weather **since** Saturday.
25. I've known Tom **since** 1990.
26. We have been waiting for the bus **for** half an hour.
27. She hasn't lost a match **since** April.
28. Things have changed **since** she's become headmaster.
29. The police have been looking for him **for** a month.
30. Our dog has been ill **for** two days.
31. I've been looking for this book **for** a long time.
32. I've been working **since** I got up.
33. The kettle has been boiling **for** ten minutes.
34. They have been living in Madrid **since** 1972.
35. He has been in prison **for** four years.
36. He has known about the fact **for** a long time.
37. Conditions have changed a lot **since** we were children.
38. Our teacher has been very ill **for** the last month.
39. I haven't eaten anything **for** twenty-four hours.
40. In fact he is always very rude. We have been waiting for him **for** half an hour.
41. I haven't seen him for three years. It is because I haven't been there **since** I left school.
42. I have been trying to mend this old fashioned car **for** hours.
43. One of my friends has been teaching in Tokyo **for** three years. I haven't met him since last year.
44. I haven't enjoyed myself **for** two weeks since I heard that my final exam grades were low.
45. I know that you have never seen a lion **since** you were born. Then now I say that we can go to the zoo and see one.
46. The police have been looking for him for two weeks **since** he escaped from the prison.
47. He hasn't spoken to me even a word **since** the last meeting.
48. I haven't phoned him **for** a week.
49. He has been the principal of our high school **since** 1988.
50. Dean has been learning Japanese **for** two years.
51. I have been waiting **since** 4 o'clock.
52. Sue has only been waiting **for** 20 minutes.
53. Tim and Tina have been learning English **for** six years.
54. Fred and Frida have been learning French **since** 1998.
55. Joe and Josephine have been going out together **since** Valentine's Day.
56. I haven't been on holiday **since** last July.
57. Mary has been saving her money **for** many years.
58. I haven't eaten anything **since** breakfast.
59. You have been watching TV **for** hours.
60. We have been living here **for** 2 months.
61. What have you been doing **since** we last spoke?
62. What has changed in your life **since** you moved here?
63. I have been working full-time **for** several weeks now.
64. Donald hasn't wanted to talk to me **since** our argument.
65. Tony Swanson has been with the company **for** 25 years.
66. The little girl was hungry because she hadn’t eaten anything **for** a while.
67. Puerto Ricans have been migrating to the United States **for** over a century.
68. Human beings have sought to know the unimaginable **since** the beginning of time.
69. It is believed that everything in the universe has existed **since** the Big Bang 15 billion years ago.
70. Is there a family member who has a talent that has been in your family **for** several generations?
71. The weather is dry. It hasn't rained **for** a few weeks.
72. It's been raining **since** lunchtime.
73. Sarah has lived in Paris **since** 1995.
74. Paul has lived in London **for** 10 years.
75. I'm tired of waiting. We've been sitting here **for** an hour.
76. Kevin has been looking for a job **since** he left school.
77. I haven't been to a party **for** ages.
78. I wonder where Joe is. I haven't seen him **since** last week.
79. Jane is away. She's been away **since** Friday.
80. We're going to France **for** a month next summer.
81. Beckett's Ice Cream Shop has been in business **since** 1942.
82. We've lived in this house **for** five years.
83. Jim has had a cold **since** last Thursday and hasn't been able to go to work.
84. No wonder Seth is tired. He hasn't slept **for** 24 hours!
85. Monica hasn't heard from her son **since** last Thursday.
86. Paul will be studying at Yale **for** another semester.
87. I haven't been to St. Petersburg **since** 1995.
88. How long are you here **for**?
89. Meg has worked at IBM **for** ten years.
90. I have been working here **for** a fortnight.
91. He has been ill **since** Monday.
92. Sarah's father has been a policeman **for** 20 years.
93. David has had a driving licence **since** 1980.
94. He has been Prime Minister **for** six months.
95. You've been on the phone **for** half an hour.
96. They have lived here **for** five years.
97. He has been unemployed **since** April.
98. It hasn't snowed **since** 2021.
99. He has smoked a pipe **for** 20 years.
100. The pizza has been in the oven **for** 10 minutes.
101. I have been waiting for you **for** 2 hours.