Let's simplify the expression step by step:

1. Recognize the expression:
\[
627 \times 64 + 57 \times 37 \times 11 - 600 - 27627 \times 64 + 57 \times 37 \times 11 - 600 - 27
\]

2. Combine like terms. Notice \( 57 \times 37 \times 11 \) appears twice:
- The sum of the two \( 57 \times 37 \times 11 \) terms is:
\[
2 \times (57 \times 37 \times 11)
\]

3. Rewrite the expression:
\[
(627 - 27627) \times 64 + 2 \times (57 \times 37 \times 11) - 1200 - 27
\]

4. Calculate \( 627 - 27627 \):
\[
627 - 27627 = -27000
\]

5. Substitute back into the expression:
\[
-27000 \times 64 + 2 \times (57 \times 37 \times 11) - 1200 - 27
\]

6. Calculate \( -27000 \times 64 \):
\[
-27000 \times 64 = -1728000
\]

7. Calculate \( 57 \times 37 \times 11 \):
- First, compute \( 57 \times 37 = 2109 \)
- Then, compute \( 2109 \times 11 = 23299 \)

8. Now, calculate:
\[
2 \times 23299 = 46598
\]

9. Combine everything:
\[
-1728000 + 46598 - 1200 - 27
\]

10. First combine \( -1200 - 27 = -1227 \).

11. Now, calculate:
\[
-1728000 + 46598 - 1227
\]

12. Combine \( -1728000 + 46598 \):
\[
-1728000 + 46598 = -1724402
\]

13. Finally:
\[
-1724402 - 1227 = -1725629
\]

Thus, the final answer is:
\[
\boxed{-1725629}
\]